Cannabis Sativa CBD Extract Shows Promising Antibacterial Activity Against Salmonella Typhimurium and S. Newington

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The increased prevalence and occurrence of antimicrobial resistance is a major health concern worldwide, making the development of novel antibacterial treatment methods essential to the preservation of public health. Remarkably, CBD extracted from C. sativa has demonstrated potential antibacterial activity against a common Gram-negative bacterial pathogen, Salmonella. CBD, initially not recognized as an active compound of cannabinoids, has been shown to possess potential therapeutic benefits.

To evaluate the extent of CBD’s potential, a recently published peer-reviewed scientific article Cannabis sativa CBD Extract Shows Promising Antibacterial Activity against Salmonella typhimurium and Salmonella newington has provided insight into unique antibacterial potential of CBD against Salmonella newington and Salmonella typhimurium.

The article, published in Molecules, a leading journal of synthetic chemistry and natural product chemistry, examines the bacterial response of Salmonella newington and Salmonella typhimurium to CBD exposure through biological assays, bacterial kinetics, and fluorescence microscopy.

The research provides three key findings:

  • Zones of inhibition around the CBD-treated disks suggest inhibition of bacterial growth due to exposure to CBD
  • Salmonella newington might have a greater susceptibility to CBD than Salmonella typhimurium
  • CBD and ampicillin both successfully inhibited Salmonella growth in both strains to a similar extent
Various Conentrations of CBD on Salmonella Typhimurium and S. Newington
Various Conentrations of CBD on Salmonella Typhimurium and S. Newington

The graph above measures the effect of varying concentrations of CBD on Salmonella typhimurium and Salmonella newington and found that both Salmonella typhimurium and Salmonella newington cultures treated with CBD showed a significant reduction in optical density within 6 h of treatment, signifying that CBD extract does exhibit antibacterial characteristics. It was even observed that in Salmonella newington, CBD at a concentration as low as 0.0125 μg/mL reduced bacterial growth over the 6 h period, suggesting that Salmonella newington might have a greater susceptibility to CBD than Salmonella typhimurium.

The article also reports that Salmonella resistance to CBD might be conferred through a different mechanism than antibiotic resistance, posing the question of CBD–antibiotic co-therapy as a potential novel application.

This research has significant implications for the potential of CBD as a therapeutic and antibacterial agent and demonstrates the effectiveness of CBD against Salmonella typhimurium and Salmonella newington.

To purchase high quality, clinically tested CBD products, visit our shop. To acquire more information about how CBD can be beneficial to you, contact Verséa Wellness specialists at +1 (800) 397-0670 or info@getversea.com.

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